Springwise has listed its top 5 of non-profit / cause-related ideas from 2006. Worth a look, even if we have covered some of the previously.
And for a more wide-ranging, deep-thinking take on what lies ahead, check out the Edge question of 2007: what are you optimistic about? and why? Richard Dawkins, GIB patron Brian Eno, Cory Doctorow, Craig Venter, Steven Pinker and many more give their answers online. Makes for interesting, occasionally enlightening, and slightly uneven reading. But well worth the time.